• Studies carried out with LTRAs before

  2019-07-02

  

  Studies carried out with LTRAs before the identification of the CysLT2R, showed a controversial picture, as results that suggest a role for cysteinyl-LTs in the expansion of ischemic damage and in cardiac dysfunction during reperfusion [5], [68], [69] were evenly balanced by others suggesting that t

• br Introduction Alzheimer s disease AD is

  2019-07-02

  

  Introduction Alzheimer’s disease (AD) is the progressive version of mild cognitive impairment and usually met by the elderly population. It falls into the class of neurodegenerative disorders that attacks the nociceptin receptor nerves cells, or neurons, resulting in loss of memory, impairment o

• Introduction Progesterone also known as

  2019-07-02

  

  Introduction Progesterone, also known as P4, is a steroid hormone acting as a key component in the complex regulation of female reproductive function. P4 plays major physiological roles in the uterus and ovary by releasing mature oocytes helping in implantation and maintenance of pregnancy, as well

• The serotonin transporter gene encodes

  2019-07-02

  

  The serotonin transporter gene () encodes an integral membrane protein that transports serotonin from the synaptic spaces into the presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent way. This protein is a target of psychomotor stimulants

• br Acknowledgements br Introduction Supramolecular collagen

  2019-07-02

  

  Acknowledgements Introduction Supramolecular collagen assemblies are crucial for the mechanical stability of animal bodies (Myllyharju and Kivirikko, 2004). The basic collagen structure is a triple helix of three chains containing multiple Gly-X-X\' repeats; X and X\' are often proline and 4-h

• Nutlin-3 what A growing number of other post

  2019-07-02

  

  A growing number of other post-translational modifications are implicated in regulation of the ubiquitin system, including substrate modification by hydroxylation, glycosylation, acetylation, methylation, modification by poly(ADP-ribose) (PAR), and attachment of ubiquitin-like modifiers. The HIF1-α

• The mechanism underlying the increased PON levels found in

  2019-07-01

  

  The mechanism underlying the increased PON1 levels found in greenhouse workers may be accounted for by an increased protein BCH following pesticide interaction with different nuclear receptors as also occurs with other chemicals, such as polyphenols and statins [28]. A number of nuclear receptors

• Target of emotional drivers of preventive and treatment

  2019-07-01

  

  Target of emotional drivers of preventive and treatment behaviours is a promising avenue for increasing the effectiveness of behaviour change interventions. More research is needed on how to best operationalise interventions based on emotional drivers in routine programmatic settings, how to measure

• In conclusion we observed that the

  2019-07-01

  

  In conclusion, we observed that the rate of carbapenem-resistant A. baumannii was high among burn patients. In addition, the most effective drugs against A. baumannii in vitro were colistin and polymyxin B. Since resistant isolates only had blaOXA-23-like and blaOXA-24-like, it seems that carbapenem

• br Sustained monomorphic ventricular tachycardia br Monomorp

  2019-07-01

  

  Sustained monomorphic ventricular tachycardia Monomorphic VT is defined as sustained when lasting longer than 30s or requires earlier intervention due to haemodynamic instability [89]. Most commonly, sustained MMVT occurs in the setting of diseased myocardium, but may also be idiopathic, occurr

• Early recognition of ICD lead malfunction is desirable to pr

  2019-07-01

  

  Early recognition of ICD lead malfunction is desirable to prevent the life-threatening consequences of lead failure. Recent reports indicate that the majority of patients with ICD lead failure experience inappropriate ICD therapies, often as the presenting problem [4,6]. Regular device interrogation

• The GCT usually involves a cladding

  2019-07-01

  

  The GCT usually involves a cladding that consisted of reactive bone and fibrosis, with a distinct boundary surrounded by soft tissue. Nevertheless, the active cladding is very thin among patients with severe invasiveness, including tumors that extend directly in into the muscle and fat, or other sig

• br Mechanisms of arrhythmias Several schemes have

  2019-07-01

  

  Mechanisms of arrhythmias Several schemes have been used to classify the mechanisms of cardiac arrhythmias. Traditionally, these have been divided into nonreentrant and reentrant activity [11]. An alternative scheme divided them into those occurring at the cellular and tissue levels [12]. A dynam

• br Therapy for the CPVT br

  2019-07-01

  

  Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele

• br Implementation of a programme called the the key componen

  2019-07-01

  

  Implementation of a programme called the , the key component of the UNICEF/WHO Baby-Friendly Hospital Initiative (BFHI) increases exclusive breastfeeding at 3 months, any breastfeeding at 12 months, and reduces diarrhoeal disease. These outcomes were shown in a cluster-randomised study of 31 hospi

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